answers:

I believe, tho i’m not certain, you can run more than a single brushless motor through an esc with a simply split cable. It’s not done for 2 good reasons.
The amperage the motors would draw would require you to have an incredibly high amp rated esc to deal with the current, the largest generally made is 150 amps constant. Any more than this and it would require more than one esc.
A single brushless motor would be sufficient to really shift something, 4 strikes me as over kill.
I guess you have 2 options. The first would be to run all 4 props through a belt from a single motor. Or, have 4 small (370 size) brushless motors, which should give the power required, without frying the esc. (Hopefully, check the draw, under load, of the motors before buying, the amps must add up to less than your ESCs max rating!)
The last thing that occurs is that you would need a lipo, that is very high C rating, therefore very big, therefore very heavy, therefore inconvenient for a model required to fly.
This is all summise, i hope significantly smarter people will correct any mistakes ive surely made.